Tag Archives: wine

Families torn by grief because of a drunk driver on the 403 going in the wrong direction. This madness must end!

This is why the laws must be changed. A life has been snubbed out because of a possible drunk driver. I am not sure how one can justify going in the wrong direction on a provincial highway? The way the laws stand he will probably get a “slap on the wrist”, if convicted in Ontario. I am not sure how anyone can condone these actions anymore. If any political leaders are listening, its time for the laws to change, now and protect the public against this serious and unforgiving offense.
Several years ago, before he moved to Canada, met his wife and had two beautiful daughters, Herminio Del Valle was told in a dream not to drive.

So he never bought a car, thinking all the while he was preventing a horrible accident.

To get to work, he turned to long-time pal Pablo Guzman, who had also emigrated from the Dominican Republic and got Del Valle his job at a Burlington aluminum factory. A trusted employee, Guzman was given the keys to the factory to open the shop early each morning.

That’s how the two men found themselves on Hwy. 403 in Mississauga around 4:45 a.m. Friday, when an allegedly drunk driver in a pickup truck going in the wrong direction hit their car head-on. “He was always driving people here and there,” Guzman’s friend, Patricia Moreno, said inside his Woodbridge home yesterday, Guzman’s crying wife, Rocio, and three children sitting next to her.

“Especially widows. He was always helping them,” she said, her voice drowned out by sobs. “Now, she’s a widow.” About 15 km south in North York, Del Valle’s widow, Carmen, sat with daughters Catherine, 9, and Natalie, 7, surrounded by family who had flown in from the U.S.

“Everything was for his family,” a shattered Carmen said in Spanish with a family member translating. Carmen had arrived at the Guzman home hours after the crash Friday with condolences, only to learn her husband was also dead.

“My dad was the best daddy,” Catherine said, tears rolling down her cheeks. “He used to try to get me the stuff that I need.”

Each of Guzman’s children — Victor, 8, Gleny, 6, and Santiago, 4 — have been coping in different ways.

“Where’s daddy?” Victor asked Moreno yesterday. “Heaven,” she said.

“I want to go to the CN tower to be closer to daddy,” he replied.

Gleny was found in her closet Saturday, holding a dress her dad had just bought for her.

Santiago clutched a toy truck in his hand while he sat on his mother’s lap.

“He knows it was a truck,” Moreno said. “So he says that truck killed his dad.”

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Secret of red wine revealed

It’s an enzyme called Aldehyde dehydrogenase. Specifically it’s a version of this enzyme designated as ALDH-2. Used to burn off alcohol in the liver, it also acts against toxins released when fats break down during a heart attack.

Now a team led by Stanford researchers has created a synthetic version of the enzyme, aldA-1, that could mimic the effect upon injection and help the enzyme do its job.

One plan would be to inject it along with nitroglycerin, helping those 40% of East Asians who don’t respond well to that drug. But here is a clue — those same people can’t handle their alcohol.

Thomas Hurley of Indiana University, who worked on the study, said aldA-1 works by signaling ALDH-2 directly to get to work protecting the heart muscle in breaking down fats.

By repairing damaged fats during a heart attack, the enzyme keeps cells from dying, reducing the actual damage to the muscle. The synthetic version may also re-activate ALDH-2 molecules that have mutated.

In the study of aldA-1, the team found that damage to rat hearts was cut by 60% when the synthetic enzyme was used.

Heartwire contacted Dr. Eric Topol of the Scripps Research Institute, who noted that many chemicals have been found to work in studies of rats, like this study, but were later found not to work in people.

Still, even he said this deserves a follow-up.

Pharmacologist Daria Mochly-Rosen of Stanford, who headed the study, said the finding may also help in the treatment of other diseases caused by malfunctioning ALDH-2, including Alzheimer’s.

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