Tag Archives: Hope

Marrow transplant may have cured AIDS, German doctors say


Provided by: The Canadian Press
Written by: Patrick Mcgroarty, THE ASSOCIATED PRESS
Nov. 12, 2008
BERLIN – An American man who suffered from AIDS appears to have been cured of the disease 20 months after receiving a targeted bone marrow transplant normally used to fight leukemia, his doctors said Wednesday.

While researchers – and the doctors themselves – caution that the case might be no more than a fluke, others say it may inspire a greater interest in gene therapy to fight the disease that claims two million lives each year. The virus has infected 33 million people worldwide.

Dr. Gero Huetter said his 42-year-old patient, an American living in Berlin who was not identified, had been infected with the AIDS virus for more than a decade. But 20 months after undergoing a transplant of genetically selected bone marrow, he no longer shows signs of carrying the virus.

“We waited every day for a bad reading,” Huetter said.

It has not come. Researchers at Berlin’s Charite hospital and medical school say tests on his bone marrow, blood and other organ tissues have all been clean.

However, Dr. Andrew Badley, director of the HIV and immunology research lab at the Mayo Clinic in Rochester, Minn., said those tests have probably not been extensive enough.

“A lot more scrutiny from a lot of different biological samples would be required to say it’s not present,” Badley said.

This isn’t the first time marrow transplants have been attempted for treating AIDS or HIV infection. In 1999, an article in the journal Medical Hypotheses reviewed the results of 32 attempts reported between 1982 and 1996. In two cases, HIV was apparently eradicated, the review reported.

Huetter’s patient was under treatment at Charite for both AIDS and leukemia, which developed unrelated to HIV.

As Huetter – who is a hematologist, not an HIV specialist – prepared to treat the patient’s leukemia with a bone marrow transplant, he recalled that some people carry a genetic mutation that seems to make them resistant to HIV infection. If the mutation, called Delta 32, is inherited from both parents, it prevents HIV from attaching itself to cells by blocking CCR5, a receptor that acts as a kind of gateway.

“I read it in 1996, coincidentally,” Huetter told reporters at the medical school. “I remembered it and thought it might work.”

Read More

Vote for Hope – Obama 2008 Video


With the 2008 presidential election, Americans face a pivotal choice between not just two candidates, but two paradigms. We need someone who understands the complexity of our time. Someone who believes in investing in renewable energy, in education, in women’s rights, in civil rights, in healthcare for Americans. Someone who believes in dealing with global issues with diplomacy so we can restore our respect in the world. Barack Obama represents the change we need and can lead us into a brighter future.


“Vote For Hope” was written to encourage and inspire the hip hop generation—and everyone—to get involved, and contribute their time, energy, creativity, and other resources to be the change they want to see in the world. We have been inspired by the artistic and musical contributions that have been pouring out accross the nation in support of Barack Obama’s campaign. Vote for Hope is our offering to this creative movement. It is our way of adding our small voice to the collective voice of millions of Americans calling for a change.

See more…

Layton appeals to Quebec voters


RICHARD BRENNAN
OTTAWA BUREAU
GATINEAU—NDP Leader Jack Layton today urged Quebec voters to turn their backs on the separatist Bloc Quebecois.

“There’s a new choice for Quebec in this election – a choice of hope and optimism,” he said, adding the province would benefit in many ways from a national party, as opposed to one that has no MPs outside Quebec.

Layton pointed out many things that Quebecers hold dearly, such as the environment, that require strong actions across provincial boundaries that can only be offered by a national party.

The NDP is hoping to make a breakthrough in the riding of Gatineau with Francoise Boivin, a former Liberal MP in the Paul Martin/s Liberal government. The riding is now held by the PQ’s Richard Nadeau.

Throughout the election, Layton has been appealing to voters of all political stripes to side with the NDP, promising a New Democratic government would kill the Conservatives’ $50 billion corporate tax cut and use that money to improve child care, hire nurses and doctors, and bring in pharmacare, among other things.

Earlier in the day in Toronto, the NDP campaign turned to veteran New Democrat war horse Ed Broadbent to shore up support.

“It is good news for the NDP in every part of the country,” he told the adoring crowd, adding that the party is challenging in 20 ridings where the NDP have never been a contenders.

“We will bring in new seat after seat and we will have the largest caucus in the history (of the party),” Broadbent, who had a record 43 seats in 1988, told about 400 supporters.

read more | digg story

Sen. Edward Kennedy has a brain tumor


BOSTON – Sen. Edward M. Kennedy has a malignant brain tumor. Doctors for the Massachusetts Democrat say tests conducted after Kennedy suffered a seizure this weekend show a tumor in his left parietal lobe. Preliminary results from a biopsy of the brain identified the cause of the seizure as a malignant glioma, they said. Some experts gave the liberal lion less than a year to live.
Edward "Ted" Kennedy

Doctors discovered the tumor after the 76-year-old senator and sole surviving son of America’s most storied political family suffered a seizure over the weekend. The diagnosis cast a pall over Capitol Hill, where the Massachusetts Democrat has served since 1962, and came as a shock to a family all too accustomed to sudden, calamitous news.

“Ted Kennedy and the Kennedy family have faced adversity more times in more instances with more courage and more determination and more grace than most families have to,” said Sen. John Kerry, D-Mass. “Every one of us knows what a big heart this fellow has. He’s helped millions and millions of people — from the biggest of legislation on the floor to the most personal.”

Kerry added: “This guy is one unbelievable fighter.”

Kennedy’s doctors at Massachusetts General Hospital said he had a malignant glioma in the left parietal lobe, a region of the brain that helps govern sensation, movement and language.

Seizures can be caused by a wide variety of things, some of them relatively minor. The finding of a brain tumor — and specifically a glioma, an especially lethal type — was about the worst possible news.

Kennedy’s doctors said he will remain in the hospital for the next couple of days as they consider chemotherapy and radiation. They did not mention surgery, a possible indication the tumor is inoperable.

Outside experts gave him no more than three years — and perhaps far less.

“As a general rule, at 76, without the ability to do a surgical resection, as kind of a ballpark figure you’re probably looking at a survival of less than a year,” said Dr. Keith Black, chairman of neurosurgery at Cedars-Sinai Medical Center in Los Angeles.

In a statement, Dr. Lee Schwamm, vice chairman of neurology at Massachusetts General, and Dr. Larry Ronan, Kennedy’s primary physician, said the senator “has had no further seizures, remains in good overall condition, and is up and walking around the hospital.”

“He remains in good spirits and full of energy,” the physicians said.

An Associated Press photographer who was given access to the senator on Tuesday captured Kennedy, dressed in a gray sweater and dark slacks, joking and laughing with family members as he sat at a table in a family room at the hospital.

Kennedy’s wife since 1992, Vicki, and his five children and stepchildren have been at his bedside.

“Obviously it’s tough news for any son to hear,” said Robin Costello, a spokeswoman for one of Kennedy’s sons, Rep. Patrick Kennedy, D-R.I. “He’s comforted by the fact that his dad is such a fighter, and if anyone can get through something as challenging as this, it would be his father.”

Kennedy, the Senate’s second-longest serving member, was re-elected in 2006 and is not up for election again until 2012. Were he to resign or die in office, state law requires a special election for the seat 145 to 160 days afterward.

Among the potential Democratic candidates: Martha Coakley, the state’s attorney general; Rep. Edward J. Markey; former Rep. Joseph P. Kennedy II, Kennedy’s nephew; and Kennedy’s wife. The Republican contenders could include former Gov. Mitt Romney or former Lt. Gov. Kerry Healey.

Kennedy has left his stamp on a raft of health care, pension and immigration legislation during four decades in the Senate.

Senators of both parties heard about Kennedy’s condition during their weekly, closed-door policy lunches, and some looked drawn or misty-eyed.

read more | digg story

Senator Kennedy endorsement of Obama – Time for change!