Tag Archives: Doctor

Marrow transplant may have cured AIDS, German doctors say


Provided by: The Canadian Press
Written by: Patrick Mcgroarty, THE ASSOCIATED PRESS
Nov. 12, 2008
BERLIN – An American man who suffered from AIDS appears to have been cured of the disease 20 months after receiving a targeted bone marrow transplant normally used to fight leukemia, his doctors said Wednesday.

While researchers – and the doctors themselves – caution that the case might be no more than a fluke, others say it may inspire a greater interest in gene therapy to fight the disease that claims two million lives each year. The virus has infected 33 million people worldwide.

Dr. Gero Huetter said his 42-year-old patient, an American living in Berlin who was not identified, had been infected with the AIDS virus for more than a decade. But 20 months after undergoing a transplant of genetically selected bone marrow, he no longer shows signs of carrying the virus.

“We waited every day for a bad reading,” Huetter said.

It has not come. Researchers at Berlin’s Charite hospital and medical school say tests on his bone marrow, blood and other organ tissues have all been clean.

However, Dr. Andrew Badley, director of the HIV and immunology research lab at the Mayo Clinic in Rochester, Minn., said those tests have probably not been extensive enough.

“A lot more scrutiny from a lot of different biological samples would be required to say it’s not present,” Badley said.

This isn’t the first time marrow transplants have been attempted for treating AIDS or HIV infection. In 1999, an article in the journal Medical Hypotheses reviewed the results of 32 attempts reported between 1982 and 1996. In two cases, HIV was apparently eradicated, the review reported.

Huetter’s patient was under treatment at Charite for both AIDS and leukemia, which developed unrelated to HIV.

As Huetter – who is a hematologist, not an HIV specialist – prepared to treat the patient’s leukemia with a bone marrow transplant, he recalled that some people carry a genetic mutation that seems to make them resistant to HIV infection. If the mutation, called Delta 32, is inherited from both parents, it prevents HIV from attaching itself to cells by blocking CCR5, a receptor that acts as a kind of gateway.

“I read it in 1996, coincidentally,” Huetter told reporters at the medical school. “I remembered it and thought it might work.”

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Ontario Listeriosis Update August 22, 2008


Listeriosis

Listeriosis

Dr. David Williams, Chief Medical Officer of Health reported today that two additional deaths have been confirmed to be directly caused by the listeriosis outbreak. This brings the total number of deaths to three.Outbreak associated cases of Listeriosis have also been reported in British Columbia, Saskatchewan, and Quebec.

QUOTES

“We will continue to monitor the situation very closely,” said Dr. David Williams, Chief Medical Officer of Health. “I would like to remind the public, especially those at high risk for Listeriosis, such as the elderly, pregnant women and those with weak immune systems, to avoid consuming any meats connected with the CFIA recall. If in doubt – throw it out.”
QUICK FACTS

* Listeriosis is a reportable disease under Ontario Regulation 569 of the Health Protection and Promotion Act;
* The incubation period for Listeriosis is from three to seventy days with an average incubation period of three weeks.

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IMPORTANT UPDATE:

August 25, 2008

NEWS

The Ministry of Health and Long-Term Care’s listeriosis update, as of Monday, August 25, 2008.

The local public health units have been asked to check their local hospitals, long-term care homes and daycares to ensure that any products from the Toronto Maple Leaf plant have been removed and are not being consumed. In addition, they have also been advised to check for recalled products at key retail outlet locations.

Last Friday, the public health units were asked to check the smaller stores, mom-and-pop shops that may not have heard of the recall.

QUOTES

“I would like to remind the public to check their refrigerators and ensure that any products related to the food recall are thrown out,” said Dr David Williams, Chief Medical Officer of Health.

LEARN MORE

For an up-to-date list on this recall and other CFIA consumer food recalls online

Find out more about Listeriosis online

Contact your local public health unit.

For public inquires call ServiceOntario, INFOline at 1-866-532-3161 (Toll-free in Ontario only) Members of the media :

Mark Nesbitt, 416-314-6197
Ministry of Health and Long-Term Care
ontario.ca/health-news